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Results for "

KL 1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

4

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122720
    SEC inhibitor KL-1
    1 Publications Verification

    KL-1

    		 Others Cancer
    SEC inhibitor KL-1 (KL-1), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-1 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 3.48 μM .
    SEC inhibitor <em>KL-1</em>
  • HY-RS10569
    PIP5KL1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA)
    PIP5KL1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIP5KL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PIP5KL1 Human Pre-designed siRNA Set A
    PIP5KL1 Human Pre-designed siRNA Set A
  • HY-155972
    CRM1-IN-1

    		CRM1 Cancer
    CRM1-IN-1 (Compound KL1) is a noncovalent CRM1 inhibitor. CRM1-IN-1 induces nuclear CRM1 degradation (IC50: 0.27 μM). CRM1-IN-1 inhibits CRM1-mediated nuclear export and cell proliferation, and triggers apoptosis in colorectal cancer cells .
    CRM1-IN-1

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